What do they all have in common? Insomnia, Allergies, Anxiety, and Motion sickness

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What do they all have in common? Insomnia, Allergies, Anxiety, and Motion sickness

They are all frequently treated with a class of drugs known as anticholinergics.

Some of these drugs are available only with a prescription, but many are found over the counter, which is surprising given their ability to screw with your brain.

Anticholinergic drugs work by blocking a chemical called acetylcholine.

Below the neck, acetylcholine is responsible for involuntary muscular contractions.

This is why an anticholinergic may be prescribed to help quiet an overactive bladder.

However, in the brain, acetylcholine is critical for learning and memory, and regular use of an anticholinergic drug can cause cognitive problems in as little as sixty days.

For longer-term users (three years or more), there is a sharply increased risk of developing dementia by up to 54 percent.

Once in a while use may be okay, but keep in mind that even occasional use of a strong anticholinergic can cause acute toxicity.

Very common anticholinergic drugs

  • Dimenhydrinate is used to treat Motion sickness and is a Strong anticholinergic.
  • Diphenhydramine is an Antihistamine/sleep aid and is a Strong anticholinergic.
  • Doxylamine is also an Antihistamine/sleep aid and is a Strong anticholinergic.
  • Oxybutynin is used to treat Overactive bladder and is a Strong anticholinergic.
  • Paroxetine is used as an Antidepressant and is a Strong anticholinergic.
  • Quetiapine is also used as an Antidepressant and is a Strong anticholinergic.
  • Aripiprazole is another Antidepressant but it is a Possible anticholinergic.
  • Cyclobenzaprine is a Muscle relaxant which Moderate anticholinergic.
  • Alprazolam is an Antianxiety but Possible anticholinergic.
  • Cetirizine and Loratadine are Antihistamines that are Possibly anticholinergic.
  • Ranitidine is an Antiheartburn which is also a Possible anticholinergic.

Take note of this abridged list of the most common anticholinergic medications to avoid.

If you are currently taking any doctor’s orders, have a conversation with them about safer alternatives.


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1 thought on “What do they all have in common? Insomnia, Allergies, Anxiety, and Motion sickness

  1. Chemicals responsible for memory and learning is also responsible for the most rampant disorders of the 21st century.
    Learning never truly ends

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